Roller lifters reduce friction, which increases power.
More importantly, they allow the cam to ramp more aggressively, opening the valve faster for better flow.
But, there is a catch: To retrofit your non-roller block will require a special lifter kit and pushrods designed for the conversion. For example, Crane 11542-16 roller lifters, and 11628-16 special-length pushrods. You're probably looking at $400-500, without even including the cam.
If you want to do it, you can, but there are likely better ways to spend that kind of money, and get more gain. Of course, once you've already taken care of the other things, then maybe it's a good idea.
Joe