Now that we have an additional piece of information (the Halltech cold air intake system), I would imagine that what is occurring is that you have exceeded the performance envelope for 91 octane gas. The C5 has been highly tuned at the factory to squeeze the maximum performance with no compromises on drivability. If any of the parameters of the performance envelope get changed, there can be consequences. For example, if you are running a cold air intake system (that incorporates a ram effect, if memory serves) at high speed, you have a partial supercharger in operation.
I experienced something along the same lines with my Coupe: When I first took delivery, there was great driveability on 91 octane pump gas. Part throttle acceleration was great, and, and. During the winter and early spring of 2003 (while I was waiting for the car to be built), I was all over the C5 Modification forum. In the summer, I decided to do some serious enhancement of the drivetrain (cold air system, heads and cam, headers, etc.). I now have a significantly enhanced power output; but it didn't come free (I have to run a blend of 93 octane). When I first started driving my enhanced car, I was experiencing pinging and was generally hating the drivability of the car. My next effort was to explore what would happen if I increased the octane of the gas in an attempt to stop the pinging. After blending the 100 octane 76 gas, I have a completely transformed car. Performance is exceptional and the drivability (no pinging and no retardation of the timing with consequential loss of power output) is excellent. Yes, the blended gas does cost more and I have to plan my trips around the availability of 100 octane gas (or else drive very lightly on the go pedal until I can get back to where 100 octane gas is available).
To net out my experience, the inconvenience of having to co-ordinate the octane requirements is offset by the performance increase. This compromise may not be acceptable for other owners - it is a personal decision. The fact that Chevy only got approximately a 50 hp increase (and probably this was due to increasing the displacement to 6 liters) for the C6 would tend to indicate the compromises that had to be made to get more power and still keep drivability high on pump gas.