That might be your "experience" but experts, ie: people who work on Corvettes every day for a living recommend not using metallic anti-sieze compounds in certain situations with steel threads into aluminum holes, such as the aforementioned spark plugs.
There's another reason not to use metallic antisieze on plugs is that, if during the antisieze application you inadvertantly get any of the antisieze lube on the center electrode, the plug will misfire. Some may say, "Well, I'm really careful when I apply it." My reaction is that even a tiny bit of antisieze (which you might not even see) can cause a misfire.
The suggestion to use a little engine oil on the threads then install the plug is good advice.
If you absolutely can't bring yourself to not use antiseize, go find some DuPont Krytox antisieze, which is a non-petroleum, non-metallic product and use that.
Bottom line: there are some situations where antiseize is appropriate and there are others where it is not.
As for wheel nuts, if you use antiseize on them then torque to the manufacturer's specification---which is derived with dry threads you will over-tighten the wheel nuts. When you overtighten the nuts you create a safety problem because you will stretch the wheel studs close to yield and, in some cases, you will warp the brake disc.
